报告19例以肌无力为首发症状的慢性甲状腺功能亢进性肌病（CTM），表现为对称性、渐进性肢体近端无力伴肩、髋带肌群萎缩11例，单一肢体无力5例和重叠型肌病3例。出现高代谢综合征13伊1（68．4％），无高代谢综合征6例（31．6％），其中4例出现厌食、淡漠症状。并对其临床特点、诊断及发病机制进行了讨论。 Nineteen cases of chronic hyperthyroidism myopathy (CTM) with myasthenia as the first symptom were reported, showing symmetry, progressive proximal weakness accompanied by the shoulder, atrophy of the hip muscles, eleven cases of single limb weakness and 5 cases of overlap Myopathy in 3 cases. High metabolic syndrome 13 Iraq 1 (68.4%), no high metabolic syndrome in 6 cases (31.6%), of which 4 cases of anorexia, apathetic symptoms. And its clinical features, diagnosis and pathogenesis were discussed.