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为了评价司帕沙星对淋球菌 (NG)合并沙眼衣原体 (CT)尿道炎的治疗作用。应用荧光定量聚合酶链反应 (FQ- PCR)及涂片染色法 ,在 2 10例性传播尿道炎患者中 ,确诊了 6 3例 NG合并 CT尿道炎 ,将其随机分为 :治疗组 (A组 )单用司帕沙星治疗 ,0 .3g/ d;对比组 (B组 )用司帕沙星 0 .3g/ d加红霉素 1.0 g/ d;对照组(C组 )单用氧氟沙星 0 .4g/ d,三组均治疗 8d,对其效果及费用进行分析及统计处理。 A、B组临床治愈率分为90 .4%、95 .2 % ,两者无统计学差异 (P>0 .0 5 ) ,但治疗费用 A组较 B组明显少 ;C组临床治愈率 5 2 .4% ,与 A组有明显统计学差异 (P<0 .0 1)。提示国产司帕沙星可作为治疗 NG合并 CT尿道炎的常规药物 ,且费用较低。
In order to evaluate the therapeutic effect of sparfloxacin on Neisseria gonorrhoeae (NG) combined with Chlamydia trachomatis (CT) urethritis. Sixty-three cases of NG with CT urethritis were diagnosed in 210 cases of sexually transmitted infections of the urethritis by fluorescence quantitative polymerase chain reaction (FQ-PCR) and smear staining. They were randomly divided into treatment group (A Group) with sparfloxacin alone, 0.3g / d; control group (group B) with sparfloxacin 0. 3g / d plus erythromycin 1.0 g / d; control group (group C) alone with oxygen Ofloxacin 0. 4g / d, the three groups were treated 8d, the effect and cost analysis and statistical processing. The clinical cure rates in group A and group B were 90.4% and 95.2%, respectively, with no significant difference (P> 0.05), but the treatment cost was significantly lower in group A than in group B. The clinical cure rate in group C 5.24%, there was a significant difference with group A (P <0.01). Tip domestic sparfloxacin can be used as NG treatment of conventional urethritis urethritis drugs, and the cost is lower.