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目的观察普萘洛尔联合奥美拉唑治疗肝硬化并胃溃疡的临床效果及对临床症状的改善情况。方法选取医院2012年3月-2014年3月收治的肝硬化并胃溃疡患者80例,随机分为治疗组和对照组各40例;对照组服用奥美拉唑和维生素B6治疗,治疗组服用奥美拉唑联合普萘洛尔治疗。比较2组临床疗效及临床症状改善情况。结果治疗组患者的总有效率为92.5%显著高于对照组患者的72.5%,治疗后2组患者临床症状评分均明显低于治疗前,且治疗组低于对照组,差异均有统计学意义(P<0.05)。结论普萘洛尔联合奥美拉唑治疗肝硬化并胃溃疡患者可明显改善临床症状,提高治疗效果,值得推广及应用。
Objective To observe the clinical effect of propranolol and omeprazole in the treatment of liver cirrhosis and gastric ulcer and to improve the clinical symptoms. Methods Eighty patients with cirrhosis and gastric ulcer admitted to our hospital from March 2012 to March 2014 were randomly divided into treatment group (40 cases) and control group (40 cases). The control group was treated with omeprazole and vitamin B6 Omeprazole combined with propranolol treatment. The clinical efficacy and clinical symptom improvement in two groups were compared. Results The total effective rate of the treatment group was 92.5%, which was significantly higher than that of the control group (72.5%). After treatment, the clinical symptom scores of the two groups were significantly lower than those before treatment, and the treatment group was lower than the control group, the difference was statistically significant (P <0.05). Conclusion Propranolol combined with omeprazole in patients with liver cirrhosis and gastric ulcer can significantly improve clinical symptoms and improve the therapeutic effect, it is worth promoting and application.