蛋白S(protein S,PS)是维生素 K依赖蛋白。纯合子 PS缺乏的新生儿发生严重的血栓栓塞并发症,说明 PS在凝血系统中发挥重要作用。这些并发症和蛋白 C缺乏的纯合子发生的并发症很相似。杂合子 PS缺乏的患者成年后有发生静脉栓塞(venous thrombo embolism, VTE)的危险。血浆中 Protein S (PS) is a vitamin K-dependent protein. Severe thromboembolic complications occur in neonates lacking homozygous PS, indicating that PS plays an important role in the coagulation system. These complications are very similar to the complications of homozygous protein C deficiency. Patients with heterozygous PS deficiency are at increased risk of developing venous thrombo embolism (VTE). In plasma