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目的调查分析临床应用抗菌药物的现状,分析不合理因素,进一步规范用药。方法抽取我院随机时段的住院病人使用抗生素的全部医嘱,对抗菌药物的不合理使用情况,根据药品说明书、公开发表的国内外文献、公开出版的书籍分析、中华人民共和国药典等,再结合病例中原发病、医院感染的病原学检测结果、药品费用等因素,加以分类统计。结果存在问题:无指征用药,用药起点高,联合用药不合理等。结论抗菌药物使用亟待进一步规范,应加强对《抗菌药物临床应用指导原则》的学习及建立健全管理机制。
Objective To investigate and analyze the status quo of clinical application of antibacterials, analyze unreasonable factors and further regulate medication. Methods All hospitalized patients using antibiotics at random periods in our hospital were extracted, and the unreasonable use of antibacterial drugs was analyzed. According to the drug specification, the published literature at home and abroad, the analysis of published books, the Pharmacopoeia of the People’s Republic of China and so on, Central Plains incidence, etiology of hospital infection test results, drug costs and other factors, to be classified statistics. The results of the problem: no indications medication, medication starting point, the combination of unreasonable and so on. Conclusion The use of antimicrobial agents needs to be further regulated, and the study on “Guiding Principles of Clinical Application of Antibacterial Drugs” should be strengthened and a sound management mechanism should be established.