论文部分内容阅读
目的研究2型糖尿病(T2DM)合并冠心病(CAD)与单纯T2DM患者心电学的变化。方法以随机原则抽取行24h动态心电图(DECG)检测的单纯T2DM患者68例(Ⅰ组),T2DM合并CAD患者53例(Ⅱ组),对比分析I组和II组发生心律失常情况及心率变异性(HRV)时域指标,对其中室性早搏患者比较其窦性心率震荡(HRT)指标。结果房性心律失常发生率Ⅰ组和Ⅱ组比较,差异无统计学意义(P>0.05),但室性心律失常发生率Ⅱ组明显高于Ⅰ组(83.0%vs51.4%,P<0.05);Ⅱ组HRV时域指标SDNN〔(88.2±17.0)vs(116.5±10.7)ms,P<0.05〕,SDANNIndex〔(78.3±15.9)vs(112.6±12.3)ms,P<0.05〕,SDNNIndex〔(34.6±9.5)vs(45.5±14.3)ms,P<0.05〕,均显著低于Ⅰ组;HRT指标TO、TS值Ⅰ组和Ⅱ组比较,差异均有统计学意义(P均<0.05)。结论T2DM合并CAD患者室性心律失常发生率明显增高,HRV显著降低,HRT减弱。DECG包括HRV及HRT的检测对T2DM合并CAD患者具有重要的意义。
Objective To investigate the changes of electrocardiogram in patients with type 2 diabetes mellitus (T2DM) complicated with coronary heart disease (CAD) and simple T2DM. Methods Sixty-eight patients with T2DM (group Ⅰ) and 53 patients with type 2 diabetes mellitus (T2DM) were enrolled in this study. The arrhythmia and heart rate variability (HRV) time domain index, in which patients with premature ventricular contractions sinus heart rate turbulence (HRT) indicators. Results The incidence of atrial arrhythmia in group Ⅰ and group Ⅱ was no significant difference (P> 0.05), but the incidence of ventricular arrhythmia in group Ⅱ was significantly higher than that in group Ⅰ (83.0% vs 51.4%, P <0.05 ); SDNN (88.2 ± 17.0 vs 116.5 ± 10.7 ms, P <0.05), SDANNIndex (78.3 ± 15.9 vs 112.6 ± 12.3 ms, P <0.05) (34.6 ± 9.5) vs (45.5 ± 14.3) ms respectively, P <0.05〕, which were significantly lower than those in group Ⅰ. There were significant differences in TOT and TS between group Ⅰ and group Ⅱ (all P <0.05) . Conclusions The incidence of ventricular arrhythmia in patients with T2DM combined with CAD is significantly higher, HRV is significantly lower and HRT is weakened. The detection of DECG including HRV and HRT is of great significance to T2DM patients with CAD.