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[目的]探讨我院老年科多重耐药菌感染的临床特点,为其防治提供科学依据。[方法]对我院老年科2007年1月~2009年6月共32例多重耐药菌感染患者的临床特征、病原体的构成、药敏资料、转归等进行回顾性分析。[结果]本组多重耐药菌感染相比同期老年科住院病人的发生率为3.259%(同期老年科住院病例数982例),无一例外均属院内感染,以肺部感染为主,其发生与年龄、疾病的种类与程度、住院时间、机械通气的时间、长期使用高档抗生素等有关。其主要病原体为不动杆菌、铜绿假单胞菌、大肠埃希菌及阴沟肠杆菌,药敏监测,4类细菌广泛耐药。32例病例死亡率达62.500%。[结论]多重耐药菌感染多发生于老年人,死亡率高,应引起重视,加强住院时间管理及抗生素的合理使用监管。
[Objective] To investigate the clinical features of geriatric multi-drug resistant bacteria infection in our hospital and provide a scientific basis for its prevention and treatment. [Methods] A retrospective analysis was performed on the clinical features, pathogens, drug susceptibility data and prognosis of 32 patients with multiple drug-resistant bacterial infections in our department from January 2007 to June 2009 in our department. [Results] The incidence of multi-drug resistant bacteria in this group was 3.259% (982 cases of inpatients in the same period of geriatrics) in the same period of geriatric inpatients, both of which were nosocomial infection with pulmonary infection as the main Occurrence and age, type and extent of disease, length of stay, mechanical ventilation, long-term use of high-grade antibiotics and so on. The main pathogens are Acinetobacter, Pseudomonas aeruginosa, Escherichia coli and Enterobacter cloacae, drug susceptibility monitoring, four types of bacteria widely resistant. 32 cases of death rate of 62.500%. [Conclusion] Multiple-drug-resistant bacterial infections occur frequently in the elderly with high mortality rate, which should be paid more attention to, and to strengthen the management of hospitalized time and the rational use of antibiotics.