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当心脏呈泵衰竭时,由于几个稳定机制的活动,使周围血管阻力增高和因水、钠滞留而继发细胞外液容量扩张。曾经考虑肾素-血管紧张素-醛固酮(RAA)轴与上述反应有关,但其在心力衰竭综合征中的确切作用尚不清楚。早期研究认为有重要作用,以后的结果又认为不很肯定。然而,更好的病人选择、影响肾素释放的易变因素的控制、以及药
When the heart pump failure, due to several activities of the stability mechanism, the peripheral vascular resistance increased and water and sodium retention secondary to extracellular fluid volume expansion. It has been considered that the renin-angiotensin-aldosterone (RAA) axis is involved in the above reaction, but its exact role in heart failure syndrome is not yet known. Earlier studies found that there is an important role, the results later that are not sure. However, better patient selection, control of variables that affect renin release, and therapies