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本文报道47例正常人及176例血液病人的血清β_2-m RIA结果,ALL平均值最高,ANLL次之,MDS第三,三者都超过正常人的平均值,CAA低于正常人的平均值,因为β_2-m可由恶性细胞分泌,MDS血清β_2-m增加,支持MDS是恶性增生性血液病,因此我们认为,测定血清中的β_2-m可作为CAA和MDS鉴别诊断的一项参考指标。同时还发现,病情加重MDS血清β_2-m含量升高测定其血清中的β_2-m对预后判定有重要价值。
This article reports the serum β_2-m RIA results of 47 normal subjects and 176 blood patients, the highest average ALL, followed by ANLL, the third and the third MDS exceed the normal average, CAA lower than the normal average , Because β_2-m can be secreted by malignant cells, MDS serum β_2-m increased to support MDS is a malignant proliferative hematopathy, so we think that the determination of serum β_2-m can be used as a differential diagnosis of CAA and MDS as a reference index. At the same time, it was also found that the increased β_2-m level in serum of MDS patients was of great value in the determination of β_2-m in serum.