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目的探讨微生态制剂预防200例新生儿坏死型小肠结肠炎(NEC)早产儿的临床效果。方法选取住院部妇产科收治的200例NEC早产儿为研究对象,将其按照处理方式的不同分为两组,对照组早产儿给予纠正水电解质紊乱、酸碱失衡、禁食,并给予营养等常规对症处理,观察组早产儿给予微生态制剂预防处理,比较两组早产儿的疗效。结果观察组早产儿NEC发生率明显低于对照组,且球菌总数、杆菌总数及球杆菌比值低于对照组,差异均有统计学意义(均P<0.05)。结论采用微生态制剂对NEC早产儿的发生具有一定预防作用,能有效调控其肠道菌群比例,缩短住院时间。
Objective To investigate the clinical efficacy of probiotics in the prevention of premature infants with 200 neonates with necrotizing enterocolitis (NEC). Methods 200 preterm infants with NEC admitted to obstetrics and gynecology department of inpatient department were divided into two groups according to different treatment methods. The control group was given pretreatment to correct water-electrolyte imbalance, acid-base imbalance, fasting and nutrition And other conventional symptomatic treatment, observation group premature children given probiotics prevention and treatment, the efficacy of the two groups of premature children. Results The incidence of NEC in observation group was significantly lower than that in control group, and the total number of cocci, the total number of bacteria and the ratio of coccus were lower than those in control group (all P <0.05). Conclusion The use of probiotics can prevent preterm infants with NEC, and can effectively control the proportion of intestinal microflora and shorten the hospital stay.