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目的：探讨癌胚抗原在皮肤汗腺肿瘤中的诊断和鉴别诊断的价值。方法：应用ＡＢＣ法检测了癌胚抗原在５例胎儿皮肤、３２例成人皮肤、４５例汗腺肿瘤、５例皮脂腺肿瘤及５例毛囊肿瘤中的表达情况。结果：胎儿、成人汗腺呈腔膜型着染，阳性率为８０％和８４．４％；表皮、皮脂腺、毛囊不着染；汗腺良性肿瘤呈腔膜型着染，阳性率为６５．２％；汗腺恶性肿瘤呈腔膜型和胞浆型着染，胞浆着染形态不规则，阳性率为８０％。皮脂腺肿瘤和毛囊肿瘤染色阴性。结论：癌胚抗原是诊断汗腺来源肿瘤的一个较特异的标记物，有助于汗腺肿瘤与其它皮肤来源肿瘤的鉴别诊断。
Objective: To investigate the value of carcinoembryonic antigen in the diagnosis and differential diagnosis of skin sweat gland tumors. Methods: The expression of CEA in 5 cases of fetal skin, 32 cases of adult skin, 45 cases of sweat gland tumors, 5 cases of sebaceous gland tumors and 5 cases of hair follicle tumors were detected by ABC method. RESULTS: The fetal and adult sweat glands were stained with peritoneal membranes. The positive rates were 80% and 84.4%. The epidermis, sebaceous glands, and hair follicles were not stained. The benign gland tumors were stained with luminal membranes, and the positive rate was 65.2%. The sweat gland malignant tumors were stained by luminal and cytoplasmic types. The cytoplasmic staining pattern was irregular and the positive rate was 80%. Sebaceous tumors and hair follicle tumors stained negative. Conclusion: Carcinoembryonic antigen is a specific marker for diagnosis of sweat gland-derived tumors, which is helpful for the differential diagnosis of sweat gland tumors and other skin-derived tumors.