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有近半数的肝硬化并上消化道出血是由于门脉高压性胃粘膜病变所致,有效的止血除降门脉压外,制酸剂同样重要。本文采用垂体后叶素和洛克联合应用,结果较以往常用制酸剂甲氰咪胍疗效好,且复发率低。 1 材料和方法 材料:30例患者都为男性,均有肝硬化或首次消化道出血入院有门脉高压症候群和肝功能异常表现,入院后24～48小时作胃镜检查可见食道胃底静脉曲张,胃粘膜弥漫充血斑,呈猩红热样疹,并见糜烂,陈旧血迹和活动出血点。 治疗方法:第一组病人入院后立即静注洛赛克40mg,每天1次,连续用至大便潜血转为阴性,再改为每日口服20mg,2～4周停服,同时静点垂体后叶素10u/日至出血停止24小时后渐停止。第二组用甲氰咪胍0.6和止血芳酸0.6静点1次/日,用至大便潜血转为阴性2～3天后停药。出
Nearly half of cirrhosis and upper gastrointestinal bleeding is due to portal hypertensive gastric mucosal lesions, effective hemostasis in addition to lowering portal pressure, antacids are equally important. In this paper, the combined application of vasopressin and Locke, the results than the usual antacid cimetidine effective, and the recurrence rate is low. 1 Materials and Methods Materials: All 30 patients were male, with cirrhosis or first-episode of gastrointestinal bleeding admitted to hospital with portal hypertension syndrome and abnormal liver function. Gastroscopy of esophageal and gastric varices was observed 24 to 48 hours after admission, Gastric mucosa filled with congestion spots, was scarlet fever-like rash, and see erosion, old blood and active bleeding point. Treatment: The first group of patients intravenously immediately after admission Losec 40mg, 1 day, continuous use to fecal occult blood turned negative, and then changed to daily oral 20mg, 2 to 4 weeks to stop taking the same time point after pituitary Ye Su 10u / day to stop bleeding stop after 24 hours. The second group with cimetidine 0.6 and hemostatic aromatherapy 0.6 static point 1 / day, with fecal occult blood turned negative 2 to 3 days after the withdrawal. Out