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目的:提高药品不良反应(ADR)监测水平,为临床合理用药提供参考。方法:对我中心2008年1月～12月收集到的药品不良反应/事件(ADR/ADE)报告502例,从年龄和性别分布、药品分类、给药途径、严重的ADR以及不合理用药案例进行统计分析。结果:502例ADR/ADE中,大于60岁的患者占48.21%,抗感染药物占48.01%,严重ADR占5.98%,不合理用药导致药品不良事件(ADE)被认定为ADR的占10.16%。结论:加大合理用药宣传,加强对老年患者用药监测是以后药品不良反应工作的重点。
Objective: To improve the monitoring of adverse drug reactions (ADR) and provide a reference for clinical rational drug use. Methods: A total of 502 cases of adverse drug reactions (ADRs / ADEs) were collected from January 2008 to December 2008 in our center from the age and gender distribution, drug classification, route of administration, severe ADR and unreasonable drug use cases conduct statistical analysis. Results: In 502 cases of ADR / ADE, patients over 60 years old accounted for 48.21%, anti-infective drugs accounted for 48.01%, severe ADR accounted for 5.98%, unreasonable medication lead to ADR was identified as ADR accounted for 10.16%. Conclusion: To increase rational publicity on drug use and to strengthen drug abuse monitoring in elderly patients are the key points of adverse drug reactions in the future.