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目的观察低温血液透析对尿毒症维持性血透患者皮肤瘙痒的改善情况。方法入选我院维持性血透伴皮肤瘙痒患者65例,随机分为低温透析组和对照组。低温组每次透析时采用透析液温度为35～35.5℃,常温对照组采用37℃透析液,其它治疗方案无差别。观察皮肤瘙痒改善情况。结果低温透析组33例患者中,皮肤瘙痒显效6例,有效17例,总有效率69.7%,与对照组比较有明显统计学意义(P<0.01)。结论低温透析在一定程度上能有效缓解尿毒症患者皮肤瘙痒,且安全、经济,可作为轻度皮肤瘙痒的主要治疗方法和重度顽固皮肤瘙痒的重要辅助治疗方法。
Objective To observe the improvement of pruritus in patients with uremic maintenance hemodialysis by hypothermia hemodialysis. Methods Totally 65 patients with maintenance hemodialysis and pruritus in our hospital were randomly divided into hypothermia dialysis group and control group. The dialysis fluid temperature was 35-35.5 ℃ in dialysis group and 37 ℃ dialysate group in normal temperature group. No difference was found in other treatment regimens. Observe the skin itching to improve the situation. Results In the 33 cases of cryogenic dialysis group, pruritus was effective in 6 cases and effective in 17 cases, with a total effective rate of 69.7%. Compared with the control group, there was significant difference (P <0.01). Conclusion Low-temperature dialysis can effectively relieve pruritus of uremic patients and is safe and economical. It can be used as a primary treatment for mild pruritus and an important adjuvant therapy for severe stubborn pruritus.