[目的]探讨宫腔镜直视下活检及分段诊刮术对子宫内膜癌的诊断意义。[方法]子宫内膜癌患者300例随机分为观察组(153例)与对照组(147例),观察组行宫腔镜直视下活检及分段诊刮术,对照组行单纯分段诊刮术,观察两组术前病理诊断的准确性,宫颈受累诊断的可靠性,腹腔冲洗液细胞检测的阳性情况。[结果]观察组诊断准确性为96.73%,明显高于对照组的90.48%(P<0.05);观察组宫颈受累诊断准确性为87.50%,明显高于对照组55.56%,差异有统计学意义(P<0.05);观察组腹腔冲洗液细胞学检测阳性者6例,阳性率为3.92%;对照组细胞学检测阳性者5例,阳性率为3.40%,两组相比较差异无统计学意义(P>0.05)。[结论]宫腔镜直视下活检及分段诊刮术可明显提高病理诊断和宫颈受累情况诊断的准确性,值得临床推广。 [Objective] To investigate the diagnostic significance of hysteroscopic biopsy and segmental curettage on endometrial carcinoma. [Methods] 300 patients with endometrial carcinoma were randomly divided into observation group (153 cases) and control group (147 cases). The observation group underwent hysteroscopy under biopsy and segmental curettage, while the control group received simple segmental diagnosis Scraping surgery, observing the accuracy of preoperative pathological diagnosis, the reliability of diagnosis of cervical involvement, the positive cases of intraperitoneal washing fluid cells. [Results] The diagnostic accuracy of the observation group was 96.73%, which was significantly higher than that of the control group (90.48%, P <0.05). The diagnostic accuracy of the cervical involvement in the observation group was 87.50%, which was significantly higher than that of the control group (55.56%), the difference was statistically significant (P <0.05). In the observation group, the positive rate of intraperitoneal washing cytology in 6 cases was 3.92%. In the control group, 5 cases were positive for cytology, the positive rate was 3.40%. There was no significant difference between the two groups (P> 0.05). [Conclusion] Hysteroscopy biopsy and segmental curettage can significantly improve the accuracy of pathological diagnosis and diagnosis of cervical involvement, which is worthy of clinical promotion.