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为探讨补止冲剂对溃疡性结肠炎(UC)病人外周血5-HT和CIC的影响,我们观察了25例UC病人治疗前后外周血中5-HT和CIC的含量变化,结果表明UC病人服药前后进行比较,外周血中5-HT和CIC均有显著性的差异(P<0.01),而且治疗后的5-HT和CIC的值均达到正常范围,提示补止冲剂治疗UC与降低外周血中5-HT和CIC有一定关系,可推测补止冲剂对治疗UC作用与其清除CIC,减少补体系统的激活,阻断Ⅲ型变态反应的发生有关,同时也说明5-HT可作为UC炎症程度的辅助指标。
To investigate the effect of Buzao Granules on peripheral blood 5-HT and CIC in patients with ulcerative colitis (UC), we observed changes in peripheral blood 5-HT and CIC levels before and after treatment in 25 UC patients. The results showed that UC patients took the drug. Before and after comparison, 5-HT and CIC in peripheral blood were significantly different (P<0.01), and the values of 5-HT and CIC after treatment reached the normal range, suggesting that Buzhi granules were used to treat UC and decreased. There is a certain relationship between 5-HT and CIC in peripheral blood. It can be speculated that the effect of Buzao Granules on the treatment of UC is related to its clearance of CIC, reduction of activation of the complement system, and blocking of the occurrence of type III allergic reaction. It also shows that 5-HT can be used as UC. An auxiliary indicator of inflammation.