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目的观察黄芪桂枝五物汤加减联合α-硫辛酸对糖尿病周围神经病变(DPN)的治疗效果及作用机制。方法将60例DPN患者随机分为治疗和对照组,比较二者自觉神经病变症状和神经传导速度变化。结果治疗组DPN自觉症状和神经传导速度较对照组明显改善,二者比较有统计学意义(P<0.05)。结论黄芪桂枝五物汤联合α-硫辛酸对DPN具有治疗作用。
Objective To observe the therapeutic effect and mechanism of Huangqi Guizhi Wuwu Decoction combined with α-lipoic acid on diabetic peripheral neuropathy (DPN). Methods Sixty patients with DPN were randomly divided into treatment and control groups, and the changes of their symptoms and nerve conduction velocity were compared. Results The DPN subjective symptoms and nerve conduction velocity in the treatment group were significantly improved compared with the control group (P <0.05). Conclusion Astragalus Guizhi Wuwu Decoction combined with α-lipoic acid has a therapeutic effect on DPN.