目的探讨腹腔镜与开腹手术治疗结肠癌的近、远期疗效。方法 126例结肠癌患者依手术方式分为腹腔镜组66例与开腹手术组60例,比较2组手术时间、术中出血量、并发症、术后进食时间、住院时间、5a生存率、5a无瘤生存率和复发率。结果腹腔镜组术中出血量((165.90±28.77)mL)、进食时间((2.41±0.87)d)及住院时间((9.65±1.27)d)少于开腹手术组((189.76±37.58)mL、(4.10±1.52)d、(13.07±3.70)d)(P<0.05),手术时间((156.08±17.22)min)、并发症发生率(12.1%)、5a生存率(74.2%)、5a无瘤生存率(69.7%)、复发率(21.2%)与开腹手术组((158.99±17.60)min、11.7%、76.7%、71.7%、20.0%)比较差异无统计学意义(P>0.05)。结论与开腹手术相比,腹腔镜根治术治疗结肠癌近期疗效优势明显,远期疗效相当。 Objective To investigate the short-term and long-term effects of laparoscopy and laparotomy on colon cancer. Methods One hundred and sixty-six patients with colon cancer were divided into laparoscopic group (66 cases) and laparotomy group (60 cases) by operation method. The operative time, intraoperative blood loss, complications, postoperative eating time, hospitalization time, 5a tumor-free survival and recurrence rate. Results The amount of bleeding ((165.90 ± 28.77) mL, (2.41 ± 0.87) d) and hospital stay (9.65 ± 1.27) d in laparoscopic group were less than those in open surgery group (189.76 ± 37.58) mL, (4.10 ± 1.52) d and (13.07 ± 3.70) d, respectively. The operative time was 156.08 ± 17.22 min, the complication rate was 12.1%, the survival rate of 5a was 74.2% There was no significant difference in the 5-year disease-free survival rate (69.7%), recurrence rate (21.2%) and open surgery group (158.99 ± 17.60) min, 11.7%, 76.7%, 71.7%, 20.0% 0.05). Conclusion Compared with open surgery, laparoscopic radical mastectomy has obvious advantages in short-term curative effect and long-term curative effect.