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目的探讨某企业职工脂肪肝的患病情况。方法入选在职职工1562人为调查对象,清晨空腹静脉采血,分别测定血清总胆固醇(TC),血清甘油三酯(TC),空腹血糖(FBG),血清谷丙转氨酶(ALT),并做超声检查。采用横断面调查方法对空腹血生化检测及腹部彩超检查结果进行分析。结果企业职工脂肪肝231例,检出率14.79%,在受检年龄段脂肪肝患病率随年龄增长而增加,其中男性检出率14.50%,女性检出率6.89%,男性明显高于女性(P<0.01)。脂肪肝组的血脂和空腹血糖明显高于非脂肪肝组(P<0.01)。40～50岁为检出率最高年龄段,20～30岁为检出率最低年龄段。结论关注企业在职职工的职业健康体检,并重视对危险因素检查和干预,对改善血脂代谢,预防心血管病的发生,有着积极重要的作用。
Objective To investigate the prevalence of fatty liver in workers in an enterprise. Methods 1562 serving workers were enrolled in the study. Fasting venous blood samples were taken at early morning. Serum total cholesterol (TC), serum triglyceride (TC), fasting blood glucose (FBG) and serum alanine aminotransferase (ALT) were measured and performed ultrasonography. The cross-sectional survey method was used to analyze the results of fasting blood biochemical tests and abdominal ultrasonography. Results There were 231 cases of fatty liver in enterprise employees with a detection rate of 14.79%. The prevalence of fatty liver increased with age in the examined age group, of which the detection rate was 14.50% for males and 6.89% for females, which was significantly higher in males than in females (P <0.01). The level of blood lipid and fasting blood glucose in fatty liver group were significantly higher than those in non-fatty liver group (P <0.01). 40 to 50 years old is the highest detection rate, 20 to 30 years old is the lowest detection rate. Conclusions Concerned about the occupational health examination of the employees in the enterprise and the emphasis on the inspection and intervention of the risk factors have a positive and important effect on improving blood lipid metabolism and preventing the occurrence of cardiovascular diseases.