论文部分内容阅读
锂盐作为一种抗精神兴奋的药物已在精神病界得到广泛的使用,它不仅对各种情感障碍有一定的治疗作用,而且对情绪行为也有一定的调节作用。本文采用不同剂量的锂盐注射大鼠体内,观察其对不同脑区和血液内几种电解质的含量及心电图的影响,以便探讨锂盐的作用机制问题。 实验结果表明,大鼠注射锂盐3～5日后,锂到达各脑区。剂量增加,积蓄增多,特别是大剂量时间脑积蓄最多,达到4.18MEq/克湿重。由于锂的作用,各脑区电解质的含量均发生改变,小剂量组间脑
Lithium salt, as an anti-psychotropic drug, has been widely used in the psychiatric community. It not only has a certain therapeutic effect on various affective disorders, but also has a certain regulatory effect on emotional behavior. In this paper, different doses of lithium salt injection in rats, to observe the different brain regions and blood electrolytes content and ECG effects in order to explore the mechanism of lithium salt mechanism. The experimental results show that after the lithium salt injection in rats for 3 to 5 days, the lithium reaches various brain regions. Increased dose, increased savings, especially in large doses of brain accumulation up to 4.18MEq / g wet weight. Due to the action of lithium, the content of electrolytes in each brain area was changed, and the brain of the low-dose group was changed