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目的探讨改良式大脑半球切除治疗继发于半球广泛病变的难治性癫痫的长期疗效。方法30例患者采用改良式大脑半球切除术治疗,随访8~12 a、平均10 a,观察该手术方式的长期治疗效果。结果30例癫痫发作患者均得到有效控制,其中29例得到完全控制。26例神经功能缺失症状并不比手术前增多和加重,其中5例比手术前有不同程度的恢复。神经心理学评价均较术前有不同程度提高。结论对半球广泛性病变伴难治性癫痫的患者行病侧半球切除术,可使癫痫发作得到很好的长期控制。
Objective To investigate the long-term efficacy of modified hemispherectomy for the treatment of refractory epilepsy secondary to extensive hemispheric lesions. Methods Thirty patients underwent modified hemispherectomy. The patients were followed up for 8-12 years with an average of 10 years. The long-term therapeutic effect was observed. Results 30 patients with seizures were effectively controlled, of which 29 patients were completely controlled. 26 cases of neurological deficit symptoms did not increase and worse than before surgery, 5 cases than before surgery to varying degrees of recovery. Neuropsychological assessment were improved to varying degrees compared with preoperative. Conclusion The hemisphere hemisphere extensive lesions with intractable epilepsy patients underwent hemispherectomy, the epileptic seizures can be very good long-term control.