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硝硫氰胺有较好的杀血吸虫效果,研究它在虫体内的分布,对探讨其杀虫机制有一定意义。 ~3H-硝硫氰胺O_2N—(?)—NH—(?)—NCS比放射性强度为1.9居里/毫克分子,制成储存丙酮溶液1毫居里/毫升。放化纯度在99％以上。 用两只感染血吸虫尾蚴约1 1/2月的小白鼠,按80毫克/公斤给予非氚标记的硝硫氰胺加500微居里氚标记硝硫氰胺,一次灌胃完毕。后分别在灌药两小时及24小时后断头处死,从其肝内取出已肝移的
Nitrosaminamide has a better killing effect of schistosomiasis, its distribution in the parasites, to explore its insecticidal mechanism has some significance. The ~ 3H-nitrosamine O 2 N - (?) - NH - (?) - NCS has a specific radioactivity of 1.9 Curie / millimeter and is stored at 1 milliliter / ml in a stored acetone solution. Radiochemical purity of 99% or more. Two mice infected with cercariae of Schistosoma japonicum at about 11/2 months were given non-tritiated nitrites at a dose of 80 mg / kg plus 500 microtitre tritium-labeled nitrosamines once perfused. After two hours and 24 hours after the infusion were decapitated, removed from the liver has been transferred to the liver