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目的探讨风痛宁丸治疗类风湿关节炎的临床疗效。方法选取2010年4月-2013年7月门诊部收治的类风湿关节炎患者106例,随机分为观察组和对照组各53例。观察组予风痛宁丸治疗,对照组予西医治疗,比较2组治疗疗效。结果观察组总有效率为88.68%明显高于对照组的75.47%,差异有统计学意义(P<0.05)。2组治疗后关节功能均优于治疗前,观察组双手握力、晨僵指数、功能指数、肿胀指数及疼痛指数改善情况均优于对照组,差异有统计学意义(P<0.05);20m步行时间比较差异无统计学意义(P>0.05)。观察组不良反应发生率明显低于对照组,差异有统计学意义(P<0.05)。结论风痛宁丸治疗类风湿关节炎临床效果良好,关节功能改善明显,不良反应发生率低,值得临床推广应用。
Objective To investigate the clinical effect of Fengtongning Pills in treating rheumatoid arthritis. Methods A total of 106 patients with rheumatoid arthritis who were admitted to the outpatient department from April 2010 to July 2013 were randomly divided into observation group (53 cases) and control group (53 cases). The observation group was treated with Fengtongning Pills and the control group with Western medicine. The curative effect was compared between the two groups. Results The total effective rate in observation group was 88.68%, which was significantly higher than that in control group (75.47%), the difference was statistically significant (P <0.05). The joint function of the two groups were better than that before treatment. The grip strength, morning stiffness index, functional index, swelling index and pain index in the observation group were better than those in the control group (P <0.05) There was no significant difference in time (P> 0.05). The incidence of adverse reactions in the observation group was significantly lower than that in the control group, the difference was statistically significant (P <0.05). Conclusion: Fengtongning Pill has good clinical effect on rheumatoid arthritis, obvious improvement of joint function and low incidence of adverse reactions, which deserves clinical application.