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前列腺素(Prostaglandins,PGS)是一族含有20个碳原子的不饱合脂肪酸,根据化学结构的不同,可分为 A、B、C、E、F 等数种。30年代初 Goldba-tt 和 Euler 分别从人精液和羊精囊中分离出此类物质,并将其命名为 PGS;此后发现 PGS 不仅存在于生殖系统,还可由哺乳类动物的许多细胞合成,参与生殖、泌尿、循环、呼吸、消化、神经等多系统的生理、病理过程。60年代末发现动物、人胃内存有PGS,同期发现 PGS 具有抗溃疡作用和细胞保护作用,这些发现对于了解 PGS 在消化系统中的生理作用及其在消化系统防御机制中的地位都是十分重要的。
Prostaglandins (PGS) is a group of unsaturated fatty acids containing 20 carbon atoms. According to the different chemical structures, they can be divided into several species such as A, B, C, E, and F. In the early 1930s, Goldba-tt and Euler isolated these substances from human seminal vesicles and seminal vesicles, respectively, and named them PGS; it was later discovered that PGS is not only present in the reproductive system, but also synthesized by many cells of mammals and involved in reproduction. , urology, circulation, respiration, digestion, nerves and other multi-system physiological and pathological processes. At the end of the 1960s, PGS was found in animal and human stomachs. PGS had anti-ulcerative and cytoprotective effects in the same period. These findings are very important for understanding the physiological role of PGS in the digestive system and its status in the defense mechanism of the digestive system. of.