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BACKGROUND:Han's acupoint ncwve stimulator(HANS)has been frequently used to relieve pain by promoting the central ncrvve system's release of endogenous opioid peptides through electric stimulation to the body surface.OBJECTIVE:To investigate the pain-relieving effects of HANS,combined with patient-controlled analgesia,following neurosurgery,and to observe adverse reactions and effects.DESIGN,TIME AND SETTING:A randomized centrel observation was performed at the Department of Neurology in the First Affiliated Hospital of Gannan MeScal College(Ganzhou,Jiangxi Province,China)from January 2005 to February 2006.PARTICIPANTS:Forty patients,who were selected for craniotomy and required pain relief following surgery at the Department of Neurology in the First Affiliated Hospital of Garman Medical College(China),were included in this study.METHODS:Forty patients underwent neurosurgery and were randomly divided into two groups:patient-controlled analgesia plus HANS(+HANS,n=20)and patient-controlled analgesia(-HANS,n=20).Both groups were well matched in baseline data.Automatic syringe infusion pump ZZB-150 was the product of Nantong Aipeng Medical Instruments Co.,Ltd.(China).Patient-controlled analgesia consisted of 100 mL 0.02% lappaconitine/0.02% metoclopramide.LH-402 HANS instrument was produced in Beijing(China),with a serial number of 402183.The HANS instrumentation was used to stimulate the Hegu-Laogong acupoint on one side and Jiaogan,Shenmen penetrating Shen,Waifei,Naogan penetrating Pizhixia ear acupoints on the affected side for one hour,with 2-hour intervals.The disperse-dense wave was alternating,with a 2/100 Hz frequency of dectrical stimulation.MAIN OUTCOME MEASURE:The scores of visual analogue scale and incidence of adverse reaction were observed in two groups following surgery.RESULTS:Compared with the-HANS group,the visual analogue scale scores were remarkably lower in the+HANS group six hours after surgery(P