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将77例T2DM患者分为3组:正常白蛋白尿组(尿白蛋白排泄率≤30mg/d)、微量白蛋白尿组(为30～300mg/d)及临床白蛋白尿组(≥300mg/d)。结果:不同蛋白尿组之间在病程、血压、肌酐、TG、HDL、脂蛋白(α)、UACR及DR变发生率上均有显著性差异(P<0.05),而DR患者中DN发病率亦明显升高。结论:DN与病程、血压、血脂、UACR等因素有关,病程、UACR增加是DN、DR的重要危险因素。
77 patients with T2DM were divided into three groups: normal albuminuria group (urinary albumin excretion rate ≤30mg / d), microalbuminuria group (30 ~ 300mg / d) and clinical albuminuria group (≥300mg / d). Results: There was a significant difference (P <0.05) in the course of disease, blood pressure, creatinine, TG, HDL, lipoprotein (α), UACR and DR in different proteinuria groups Also significantly higher. Conclusion: DN is related to the course of disease, blood pressure, blood lipid, UACR and other factors. The duration of disease and the increase of UACR are important risk factors of DN and DR.