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目的:探讨血清脂蛋白-a对2型糖尿病肾病的诊断意义。方法:分三组:38例2型糖尿病无白蛋白尿患者,38例2型糖尿病微量白蛋白尿患者,36例2糖尿病大量白蛋白尿患者,均用胶乳浊度法测定血清脂蛋白-a,比较3组间血清脂蛋白-a的变化规律。结果:与2型糖尿病无白蛋白尿患者相比较,2型糖尿病微量白蛋白尿患者和2型糖尿病大量白蛋白尿患者血清脂蛋白-a明显升高,差异有统计学意义。结论:血清脂蛋白-a升高与尿白蛋白量有关,提示血清脂蛋白-a对糖尿病肾病有诊断意义。
Objective: To investigate the significance of serum lipoprotein-a in type 2 diabetic nephropathy. Methods: Three groups were divided into three groups: 38 patients with type 2 diabetes without albuminuria, 38 patients with type 2 diabetes mellitus and 36 patients with 2 diabetes mellitus with large albuminuria. The levels of serum lipoprotein-a The changes of serum lipoprotein-a in three groups were compared. Results: Compared with type 2 diabetic patients without albuminuria, serum lipoprotein-a in patients with type 2 diabetes mellitus and patients with type 2 diabetes mellitus were significantly increased, the difference was statistically significant. Conclusion: Elevated serum lipoprotein-a is associated with urinary albumin, suggesting that serum lipoprotein-a is of diagnostic significance for diabetic nephropathy.