Rolling force and rolling moment are prime process parameter of external spline cold rolling. However, the precise theoretical formulae of rolling force and rolling moment are still very fewer, and the determination of them depends on experience. In the present study, the mathematical models of rolling force and rolling moment are established based on stress field theory of slip-line. And the isotropic hardening is used to improve the yield criterion. Based on MATLAB program language environment, calculation program is developed according to mathematical models established. The rolling force and rolling moment could be predicted quickly via the calculation program, and then the reliability of the models is validated by FEM. Within the range of module of spline m=0.5-1.5 mm, pressure angle of reference circle α=30.0°-45.0°, and number of spline teeth Z=19-54, the rolling force and rolling moment in rolling process (finishing rolling is excluded) are researched by means of virtualizing orthogonal experiment design. The results of the present study indicate that:the influences of module and number of spline teeth on the maximum rolling force and rolling moment in the process are remarkable;in the case of pressure angle of reference circle is little, module of spline is great, and number of spline teeth is little, the peak value of rolling force in rolling process may appear in the midst of the process;the peak value of rolling moment in rolling process appears in the midst of the process, and then oscillator weaken to a stable value. The results of the present study may provide guidelines for the determination of power of the motor and the design of hydraulic system of special machine, and provide basis for the farther researches on the precise forming process of external spline cold rolling.