To the Editor:Surgical site infection (SSI) after the neurosurgical operation,while uncommon,is a serious complication.The prevalence of SSI has been reported in a range between 0.5％ and 8.0％,[1,2] and the risk for SSI was independently associated with the number of operations (＞1),cerebrospinal fluid (CSF) drainage,duration of operation more than 4 h,CSF leakage,venous sinus entry,American Society of Anesthesiologists score more than 2,gender,surgical purposes (non-traumatic),and other infections.[3]CSF leakage,lumbar,and extraventricular drainage were independent risk factors of SSI identified with regard to traumatic brain injury.[4] In terms of the continuing conflict in south Thailand,the patients injured from blast-induced traumatic brain injury (bTBI) have been reported.[4-6] The blast effects can cause injuries,including open-scalp wounds,skull fractures,dural tearing,and CSF leakage.[6,7] Such a wound that becomes contaminated results in SSL[7] From the literature review,there appears to be a lack of studies concing the factors associated with SSI in bTBI.The aim of this study is to explore the clinical and neuroimaging parameters associated with SSI in patients with bTBI.