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目的:通过实验分析硝苯地平联合厄贝沙坦治疗糖尿病合并高血患者的临床疗效。方法:选取我院2014年2月~2016年2月收治患有糖尿病合并高血压患者共100例,采用随机分配法将患者分为实验组和对照组,每组50例,对照组患者单纯给予糖尿病基础治疗,实验组在此基础上增加口服硝苯地平缓释片及厄贝沙坦片药物治疗,硝苯地平缓释片每次服用20mg,厄贝沙坦片每次80mg,两种药物每天服用1~3次,观察两组患者治疗前后血压变化,并记录患者药物不良反应发生情况。结果:对照组治疗有效率64%,实验组治疗有效率92%,实验组明显优于对照组,差异具有统计学意义(P<0.05)。实验组发生4例不良反应,但停药后均快速恢复正常。结论:硝苯地平联合厄贝沙坦治疗糖尿病合并高血压临床疗效显著,提高治疗有效率,具有一定推广价值。
Objective: To analyze the clinical efficacy of nifedipine combined with irbesartan in the treatment of diabetic patients complicated with hyperlipidemia. Methods: A total of 100 patients with diabetes mellitus and hypertension were selected from February 2014 to February 2016 in our hospital. The patients were divided into experimental group and control group randomly by random distribution method, 50 cases in each group. The patients in control group were given only The basic treatment of diabetes, experimental group on the basis of oral administration of nifedipine sustained-release tablets and irbesartan tablets drug treatment, nifedipine sustained-release tablets each taking 20mg, irbesartan tablets each 80mg, two drugs Take 1 to 3 times a day, observe the changes of blood pressure before and after treatment in two groups, and record the occurrence of adverse drug reactions in patients. Results: The effective rate of the control group was 64%, the effective rate of the experimental group was 92%, the experimental group was significantly better than the control group, the difference was statistically significant (P <0.05). The experimental group occurred 4 cases of adverse reactions, but quickly returned to normal after stopping. Conclusion: Nifedipine combined with irbesartan in the treatment of diabetic patients with hypertension has significant clinical efficacy and improve the efficiency of treatment, with some promotional value.