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目的探讨非洛地平缓释片治疗社区高血压临床效果。方法选取2015年1月—2016年1月受诊的45例高血压患者作为研究对象,随机分为观察组23例和对照组22例,观察组口服非洛地平缓释片,对照组服用硝苯地平缓释片,两组疗程同为6个月,比较两组血压变化状况、治疗依从性,对数据进行统计分析,P<0.05为差异有统计学意义。结果观察组总有效率高于对照组,两组比较差异有统计学意义(χ~2=4.625,P<0.05);观察组治疗依从性为80.65%,对照组为64.87%,两组比较差异有统计学意义(χ~2=3.146,P<0.05);观察组收缩压(122±11)mm Hg,舒张压(81±10)mm Hg,对照组收缩压(139±8)mm Hg,舒张压(92±11)mm Hg,两组比较差异均有统计学意义(t=5.994、3.549,均P<0.05)。结论非洛地平缓释片在治疗社区高血压患者中更具优势。
Objective To investigate the clinical effect of felodipine sustained-release tablets on community-based hypertension. Methods Forty-five hypertensive patients admitted from January 2015 to January 2016 were randomly divided into observation group (n = 23) and control group (n = 22). The observation group received oral sustained-release tablets of felodipine and the control group took nitrates Benzene release tablets, the same two courses of treatment for 6 months, comparing the two groups of blood pressure changes, treatment compliance, the data were statistically analyzed, P <0.05 for the difference was statistically significant. Results The total effective rate of the observation group was higher than that of the control group (χ ~ 2 = 4.625, P <0.05). The compliance of the observation group was 80.65% and that of the control group was 64.87% (Χ ~ 2 = 3.146, P <0.05). Systolic blood pressure (122 ± 11) mm Hg and diastolic blood pressure (81 ± 10) mm Hg in the observation group were significantly higher than those in the control group (139 ± 8 mm Hg, Diastolic blood pressure (92 ± 11) mm Hg, the difference between the two groups were statistically significant (t = 5.994, 3.549, all P <0.05). Conclusion Felodipine extended release tablets have advantages in the treatment of community-based hypertension.