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为建立阴茎海绵体压力测定（ＣＭ）方法，并探讨其测定条件及影响因素，对９例主诉阳萎的志愿者进行ＣＭ及药物性化学假体压力测定（ＰＣＭ），分别采用不同诱导灌注流率（ＩＦ）、不同剂量血管扩张剂（罂粟碱）及不同海绵体压力（ＩＣＰ）设定进行ＣＭ及ＰＣＭ。比较ＣＭ及ＰＣＭ在上述不同测定条件下所得参数：ＩＦ、维持灌流率（ＭＦ）及压力跌差（ＰＬＣ）。结果表明：ＣＭ时快速与慢速灌注测得的ＭＦ差异显著，而ＰＣＭ时无显著差异；罂粟碱为３０及６０ｍｇ时测得的ＭＦ差异显著，ＩＣＰ设定低于系统舒张压（７．８４ｋＰａ）时ＰＣＭ测得的ＭＦ显著低于１１．７６ｋＰａ与１４．７ｋＰａ时；ＰＬＣ测定值较为稳定。结论：有ＩＦ、海绵体平滑肌扩张程度、ＩＣＰ设定值等多种因素影响ＣＭ，诊断静脉性阳萎时应采用ＰＣＭ，血管扩张剂用量应充分，ＩＣＰ设定应高于系统舒张压，使得ＰＣＭ测定条件尽量恒定，减少影响测定的因素。
In order to establish the method of measuring the pressure of the penis cavernous (CM) and to explore its measuring conditions and influential factors, CM and pharmacologic chemical prosthesis pressure measurement (PCM) were performed in 9 patients complaining of impotence. Different induced perfusion Rates (IF), different doses of vasodilators (papaverine), and different sponge pressure (ICP) settings for CM and PCM. Comparison of CM and PCM parameters obtained in the different measurement conditions: IF, maintenance of perfusion rate (MF) and pressure drop (PLC). The results showed that there was significant difference between MF measured by slow perfusion and CM at MF, but no significant difference at PCM. Difference of MF measured by papaverine at 30 and 60 mg was significant, ICP setting was lower than system diastolic pressure (7.84 kPa ) PCM MF measured significantly lower than 11.76kPa and 14.7kPa; PLC measured value is more stable. CONCLUSIONS: There are many factors affecting CM such as IF, spontaneous smooth muscle expansion and ICP settings. PCM should be used in diagnosing venous impotence, the dosage of vasodilator should be sufficient, ICP setting should be higher than the system diastolic pressure, The PCM measurement conditions should be as constant as possible to reduce the factors that affect the measurement.