[目的]建立番茄中啶菌噁唑残留的高效液相色谱分析法。[方法]番茄样品经乙酸乙酯提取,C18-SPE固相萃取柱净化;高效液相色谱仪配有紫外检测器检测。[结果]该方法在0.05～100 mg/L质量浓度范围内相关系数r为0.999 9;回收率为88.69%～96.82%,相对标准偏差为2.21%～3.03%;方法检出限为0.01 mg/kg。[结论]该方法用于番茄果实中啶菌噁唑残留的测定,操作简便,结果准确。 [Objective] The research aimed to establish a HPLC method for the determination of pyridoxal in tomato. [Method] The tomato samples were extracted with ethyl acetate and cleaned up by C18-SPE solid phase extraction column. The high performance liquid chromatography with UV detector was used for detection. [Result] The correlation coefficient r was 0.999 9 in the range of 0.05 ~ 100 mg / L, the recoveries were 88.69% ~ 96.82% and the relative standard deviations were 2.21% ~ 3.03%. The detection limit was 0.01 mg / kg. [Conclusion] The method was applied to the determination of pyridine albazole in tomato fruit, with simple and convenient operation and accurate results.