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氧自由基发生剂Tert-Butylhydroperoxide(t-BHP)对小鼠体内文氏疟原虫(P.vinckei)红内期有显著的杀伤作用,但能否杀伤或抑制肝细胞内疟原虫红外期的发育,还不清楚。本文使用t-BHP处理感染约氏疟原虫子孢子的大鼠,观察该制剂对疟原虫红外期的发育有无抑制作用。
Oxygen free radical generator Tert-Butylhydroperoxide (t-BHP) has a significant killing effect on the P. vinckei red-phase in mice, but it can kill or inhibit the development of malaria parasite in the liver cells It is not yet clear. In this paper, t-BHP was used to treat rats infected with Plasmodium yoelii sporozoites to observe whether the preparation has an inhibitory effect on the development of Plasmodium in infancy.