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本文报告检测103例甲亢(其中未治愈组61例,已治愈或缓解组42例)和54名正常人(对照)的血清促甲状腺激素受体抗体(TRAb)的结果。结果表明,未治愈组病人的TRAb值显著地比正常对照组为高(P<0.001),其中超过最高正常值(14.3U/L)者占73.8%。正常人和其它6种甲状腺疾病无1例超过此值(P>0.05);但是ATD治疗缓解者的TRAb值有波动现象,而应用小剂量131I和“散瘿祛亢”汤辩证加减的治愈者则无。我们认为,TRAb值检测为甲亢的诊断和监护提供了一个极好的生化标志物。
This article reports the results of the detection of serum thyrotropin receptor antibody (TRAb) in 103 cases of hyperthyroidism (61 in the untreated group, 42 in the cured or remission group) and 54 normal controls (control). The results showed that the TRAb values of patients in the untreated group were significantly higher than those in the normal control group (P <0.001), of whom 73.8% exceeded the highest normal (14.3U / L). None of the 6 normal and 6 thyroid diseases exceeded this value (P> 0.05); however, the TRAb value of the ATD-treated remitter fluctuated. However, the use of low-dose 131I and Sanshen Qu Kang decoction added or subtracted Healer no. We believe that TRAb testing provides an excellent biochemical marker for the diagnosis and monitoring of hyperthyroidism.