以吗啡和芬太尼为代表的强阿片类药是治疗中重度癌痛的有效药物。相当一部分的癌痛患者经过抗肿瘤治疗可以使疼痛得到有效的缓解,患者可以在较长时间内停用阿片类药。作为缓释剂的美施康定(硫酸吗啡控释片)、多瑞吉(芬太尼透皮贴剂)因其能在体内维持恒定的药物浓度而具有更强的 Strong opioids, represented by morphine and fentanyl, are effective drugs for the treatment of moderate-to-severe cancer pain. A considerable portion of patients with cancer pain after anti-cancer treatment can be effective in relieving pain, patients can disable opioids for a longer period of time. As a sustained release agent of mesylate (morphine sulfate controlled-release tablets), Doris (fentanyl transdermal patch) has a stronger ability to maintain a constant drug concentration in the body