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目的应用二维斑点追踪技术(2DSTI)测定患者左室心肌分层整体纵向应变(GLS),探讨其与冠脉病变程度的相关性。方法选择2015年10月至40例经冠脉造影证实的冠心病患者(冠心病组),根据Gensini评分分为轻度病变组(<25分)、中度病变组(25~49分)、重度病变组(≥50分)。选择12例冠脉造影阴性者作为对照组(n=12)。应用2DSTI测定各组患者左室心肌内膜、中膜、外膜整体纵向应变(GLS),并进行比较。结果冠心病各组左室心肌内膜、中膜、外膜的GLS均低于对照组(P均<0.01),且左室心肌内膜、中膜、外膜GLS随病变程度加重均逐渐减小(P<0.05)。结论 2DSTI测定患者左室心肌各层的GLS与患者冠脉狭窄程度有良好的相关性。
Objective To investigate the global longitudinal strain (GLS) of left ventricular myocardium by two-dimensional speckle tracking (2DSTI) and to explore its relationship with the degree of coronary artery lesion. Methods Coronary heart disease patients (coronary heart disease group) confirmed by coronary angiography from October 2015 to October 2015 were selected and divided into mild disease group (<25 points), moderate disease group (25-49 points) according to Gensini score, Severe lesions group (≥ 50 points). Twelve patients with negative coronary angiography were selected as control group (n = 12). The total longitudinal strain (GLS) of intima, media and adventitia were measured by 2DSTI and compared with each other. Results The GLS of intima, media and adventitia of left ventricular myocardium in each group were lower than those in the control group (all P <0.01), and the GLS in the intima, Small (P <0.05). Conclusion 2DSTI determination of patients with left ventricular myocardium GLS and coronary stenosis have a good correlation.