报告一个三代10人为体型矮小、精神发育不全的家系,其中间一代为同胞姐弟通婚。对存活的4例患者作了智能测验,体格检查,染色体核型分析,皮肤纹理检查及X线,脑电图,心电图,血、尿等实验室检查。对遗传方式、临床特征及病因进行了讨论。 Reported that three generations of 10 people were short-sized and under-developed family members, and their middle generation were married to their fellow siblings. The survival of 4 patients made intelligent test, physical examination, karyotype analysis, skin texture examination and X-ray, EEG, ECG, blood, urine and other laboratory tests. The mode of inheritance, clinical features and etiology were discussed.