1983年洪涛等对兰州、锦州、山东等地的106例成人流行性腹腹泻病人的粪便进行超薄切片的电镜观察,发现101例的标本中有形态与轮状病毒一致的病毒颗粒,其直径约为75nm,内有直径为45nm的致密核心,核心周围有约20nm的双层衣壳,衣壳似由规则的、呈放射状排列的亚单位。他们用免疫电镜检查病人粪便上清液,发现大量的50nm的病毒样颗粒,其形态同脱掉衣壳后的轮状病毒的内核,呈六角形或圆形, In 1983, Hong Tao and other places of Lanzhou, Jinzhou, Shandong and other places of 106 cases of adult diarrhea in patients with abdominal diarrhea observed by ultra-thin section electron microscopy and found that 101 cases of specimens with the same morphology and rotavirus virus particles, the diameter About 75nm, there are dense core with a diameter of 45nm, around the core of about 20nm double capsid, capsid like a regular, radial arrangement of subunits. They used immunoelectron microscopy to examine the supernatant of the patient’s faeces and found that a large number of 50nm-like virus-like particles were morphologically identical to the rotavirus core, hexagonal or circular,