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病毒引起的感染可引起免疫反应,它可防止再感染。通常使用的疫苗或者是无传染性的病毒,或者是灭活了的病毒。目前国外正力图用化学方法合成免疫多肽,用作抗病毒疫苗。病毒虽小,生物学结构简单,但它是免疫学的复杂体。它含有多种抗原性组分,而每一组分又可包含多重抗原性区域。当前有许多病毒免疫的研究工作都注重于确定那些对宿主产生保护性免疫反应有重要作用的抗原性区域,并利用这种信息设计新一代的疫苗。其中利用合成的低聚肽模拟抗原区的氨基酸顺序以期引起保护性免疫反应,是注意的焦点。这种合成的病毒疫苗一旦成功,与
Infections caused by viruses can cause an immune response that prevents reinfection. Commonly used vaccines are either non-contagious or inactivated. At present, foreign countries are trying to use chemical synthesis of immune peptides, as antiviral vaccine. Although the virus is small, biological structure is simple, but it is a complex immunology. It contains multiple antigenic components, each of which can contain multiple antigenic regions. At present, many studies on virus immunity focus on identifying antigenic regions that play an important role in the host’s protective immune response and use this information to design a new generation of vaccines. Among them, the use of synthetic oligopeptides to mimic the amino acid sequence in antigenic regions in order to induce a protective immune response is the focus of attention. Once this synthetic virus vaccine is successful, and