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液相色谱-质谱联用技术是利用液相色谱高效分离和质谱强大的结构检测结合的联用技术,样品前处理简单、仪器检测灵敏度高、选择性强,可以实现化合物的定性、定量分析,在中药成分分析、结构分析、含量分析、药代学等过程中发挥重要作用。本文综述分析液相色谱-质谱联用技术在中药分析中的应用,以期对中药分析提供一定的技术支持。
Liquid chromatography-mass spectrometry (LC-MS / MS) is a combination of high performance liquid chromatography (LC) and mass spectrometry (MS). The sample preparation is simple and the instrument has high detection sensitivity and selectivity. It can achieve qualitative and quantitative analysis of compounds, In the Chinese medicine composition analysis, structural analysis, content analysis, pharmacology and other processes play an important role. This review summarizes the application of LC-MS in the analysis of traditional Chinese medicine (TCM), in order to provide some technical support for the analysis of TCM.