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肿瘤干细胞(CSC)理论的提出,为人们重新认识肿瘤的本质和起源提供了新的方向和视角。CSC能直接和间接涉及肿瘤诱发的淋巴管生成,最终促进肿瘤淋巴管转移;但CSC与淋巴管生成及淋巴管转移间的关系仍然模糊不清,且其中的诸多细节问题仍然存有争议。因此,进一步深层次了解CSC的生物学特性和功能,对于建立新的肿瘤诊断和治疗体系具有重要的现实意义和价值,也可能对肿瘤的治疗带来新的希望。
The introduction of the theory of cancer stem cells (CSCs) has provided a new direction and perspective for people to re-understand the nature and origin of tumors. CSC can directly and indirectly involve tumor-induced lymphangiogenesis and eventually promote lymphatic metastasis of the tumor. However, the relationship between CSC and lymphangiogenesis and lymphatic metastasis remains unclear, and many of the details are still controversial. Therefore, further understanding of the biological characteristics and functions of CSC is of great practical significance and value for establishing a new tumor diagnosis and treatment system, and may also bring new hope for the treatment of cancer.