强直性脊柱炎(ankylosing spondylitis,AS)是一种慢性炎症性脊柱关节炎,以骶髂关节的结构改变和脊柱受累为特征,早期以骶髂关节严重疼痛为主要症状,晚期会引起脊柱的疼痛、胸腰椎后凸畸形以及严重的功能障碍,随着疾病的进展还会引起社交功能以及心理健康的问题~([1~3])。对AS患者慢性功能损害及生存质量(quality of life,QoL)的评估能够指导临床资源分配、治疗策略的制定以及药物 Ankylosing spondylitis (AS) is a chronic inflammatory arthritis of the spine characterized by structural changes of the sacroiliac joint and spinal involvement. Severe pain in the sacroiliac joint is the predominant symptom in the early stage and spine pain is caused in the late stage , Thoracolumbar kyphosis, and severe dysfunction. As the disease progresses, it can also cause social dysfunction and mental health problems (1-3). Assessment of chronic functional impairment and quality of life (QoL) in patients with AS can guide the allocation of clinical resources, the development of treatment strategies and the management of drugs