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AIM:To compare the prevalence of Helicobacter pylori(Hpylon)infection in autoimmune thrombocytopenic purpura(AITP)patients with that of nonthrombocytopenic controls,and to evaluate the efficacy of the treatment in H pylori(+)and H pylor(-)AITP patients.METHODS:The prevalence of gastric H pylori infection in38 adult AITP patients(29 female and 9 male;median age27 years;range 18-39 years)who consecutively admittedto our clinic was investagated.RESULTS:H pylori infection was found in 26 of 38 AITPpatients(68.5%).H pylori infection was found in 15 of 23control subjects(65.2%).The difference in H pylori infectionbetween the 2 groups was not significant.Thrombocytecount of H pylori-positive AITP patients was significantlylower than that of H pylori-negative AITP patients(P<0.05).Thrombocyte recovery of H pylori-positive group was lessthan that of H pylori-negative group(P<0.05).CONCLUSION:H pylori infection should be considerecd inthe treatment of AITP patients with H pylori infection.
AIM: To compare the prevalence of Helicobacter pylori (Hpylon) infection in autoimmune thrombocytopenic purpura (AITP) patients with that of nonthrombocytopenic controls, and to evaluate the efficacy of the treatment in H pylori (+) and H pylor (-) AITP patients. METHODS: The prevalence of gastric H pylori infection in38 adult AITP patients (29 female and 9 male; median age27 years; range 18-39 years) who consecutively admittedto our clinic was investagated.RESULTS: H pylori infection was found in 26 of 38 AITPpatients (68.5%). Hpylori infection was found in 15 of 23 subjects (65.2%). The difference in H pylori infection between the 2 groups was not significant. Thrombocytecount of H pylori-positive AITP patients was significantly lower than that of H pylori-negative AITP patients (P <0.05). Thrombocyte recovery of H pylori-positive group was lessthan that of H pylori-negative group (P <0.05) .CONCLUSION: H pylori infection should be treated with treatment of AITP patients with H pylori infection.