山莨菪碱的扩血管作用机制尚不清楚,林世清等[1]研究发现,山莨菪碱能改善失血性休克时肠粘膜微循环。既往研究认为与其拮抗血管平滑肌M受体或α受体[2]相关,亦有研究发现山莨菪碱有钙拮抗作用[3]。本实验旨在观察山莨菪碱对血管舒张及收缩作用的影响,并初步探讨其作用机制。1材 Anisodamine vasodilator mechanism is unclear, Lin Shiqing et al [1] found that anisodamine can improve intestinal mucosal microcirculation in hemorrhagic shock. Past studies suggest that with its antagonistic vascular smooth muscle M receptor or α receptor [2] related to the study also found that anisodamine calcium antagonism [3]. The purpose of this study was to observe the effect of anisodamine on vasodilation and contractility and to explore its mechanism. 1 material