蟾酥是一种沿用已久的传统中药,它对多种病症具有肯定的疗效。但其毒性较大,因此设法对抗毒性,这已成为蟾酥推广使用中一个急待解决的问题。实验证明,蟾酥的不同制剂其毒性是不同的。小鼠LD_(50)是:粗制品10mg/kg,醇提取物208mg/kg。水提取物900mg/kg。无论LD_(100)或LD_(50)的蟾酥,山莨菪碱均可使其小鼠毒性反应与死亡率显著降低。心电图结果表明蟾酥可使大鼠和家兔出现心率显著变慢,节律不齐,大 The wolfberry crisp is a traditional Chinese medicine that has been used for a long time and it has a positive effect on various diseases. However, its toxicity is high, so it has been tried to combat toxicity. This has become an urgent issue to be solved in the promotion of wolfberry. Experiments show that the different preparations of konjac have different toxicity. The mouse LD_(50) was: crude product 10 mg/kg, alcohol extract 208 mg/kg. Water extract 900mg/kg. Either LD 100 or LD 50, anisodamine can significantly reduce the toxicity and mortality of mice. Electrocardiogram results show that wolfberry crisp can make rats and rabbits appear significantly slower heart rate, irregular rhythm, large