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目的探讨中文版风湿病治疗依从性问卷(CCQR)的信度和效度。方法选择2010年1月—2011年12月在玉溪市人民医院风湿科住院,出院诊断为类风湿关节炎的患者54例,通过翻译风湿病治疗依从性问卷(CQR)原文并根据中国文化进行调整后制定出CCQR。间隔2～4周重复问卷,应用组内相关系数来评估CCQR的信度。采用药房处方数据评估患者治疗的现实依从性,通过确定CCQR评分和患者现实依从性的相关情况来评价CCQR的效度。结果 54例患者完成了第1次问卷调查,4例拒绝接受第2次调查,2例失访,最终48例患者完成第2次问卷调查。第1次平均CCQR评分为(57.7±19.8)分,第2次平均CCQR评分为(60.2±17.0)分,两次CCQR评分的组内相关系数为0.994〔95%可信区间为(0.990,0.997)〕。采用Pearson相关分析显示,CCQR评分与患者的现实依从性呈正相关(R2=0.635,P=0.000)。结论 CCQR是评估我国类风湿关节炎患者治疗依从性的可靠、有效的工具。
Objective To investigate the reliability and validity of the Chinese version of the Rheumatism Regulatory Compliance Questionnaire (CCQR). METHODS: From January 2010 to December 2011, 54 patients were diagnosed as rheumatoid arthritis in Yuxi People’s Hospital of Rheumatology. The translation of rheumatic diseases compliance questionnaire (CQR) was translated and adjusted according to Chinese culture After the development of CCQR. Intervals of 2 to 4 weeks were repeated questionnaires, the correlation coefficient within the group to assess the reliability of CCQR. The pharmaco-prescription data was used to assess the actual compliance of the patient’s treatment and the CCQR’s validity was assessed by determining the CCQR score and the patient’s actual compliance. Results 54 patients completed the first questionnaire, 4 refused to accept the second survey, 2 lost to the final 48 patients completed the second questionnaire. The first average CCQR score was (57.7 ± 19.8) points, the second average CCQR score was (60.2 ± 17.0) points and the two CCQR scores were 0.994 (95% confidence interval, 0.990, 0.997 )]. Pearson correlation analysis showed that there was a positive correlation between CCQR score and patients’ actual compliance (R2 = 0.635, P = 0.000). Conclusion CCQR is a reliable and effective tool to evaluate the treatment compliance of patients with rheumatoid arthritis in China.