【摘 要】
：
Pioglitazone is an oral anti-hyperglycemic agent. It is used for the treatment of diabetes mellitus type 2. It selectively stimulates nuclear receptor peroxisom
【机 构】
：
Department of Pharmaceutical Analysis,National Center for Mass Spectrometry
论文部分内容阅读
Pioglitazone is an oral anti-hyperglycemic agent. It is used for the treatment of diabetes mellitus type 2. It selectively stimulates nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR-gamma). It was the tenth-best-selling drug in the U.S. in 2008. This article examines published analytical methods reported so far in the literature for the determination of pioglitazone in biological samples and pharmaceutical formulations. They include various techniques like electrochemical methods, spectrophotometry, capillary electrophoresis, high-performance liquid chromatography, liquid chromatography-electrospray ionization-tandem mass spectrometry and high-performance thin layer chromatography.
其他文献
山阳煤矿回风立井井筒掘进到214m深时，工作面开始涌水，涌水量54.8～86m3/h，无法进行掘进工作。根据对涌水情况和地质条件的分析，决定采用工作面预注浆技术治理涌水。经工作面预注浆
目的：探讨手术室无缺陷护理模式在手术室护理实践中的应用效果。方法手术室开展的200台手术,其中2013年1~6月的100台常规护理手术作为对照组,2013年7~12月的无缺陷护理开展后1
诊断度是多处理器系统互连网络能够诊断的最大故障结点的个数，它是度量多处理器系统故障诊断能力的一种参数。早好邻条件诊断度是2012年提出的一种新的诊断度，它要求每个非故障
本文主要通过对三角形内角和定理的证明过程中呈现出不严谨的问题阐述如何提升教师的教学能力。
职业院校大发展的同时,学生基础参差不齐,数学教学工作面临了一定的困境,本文阐述了产生这一现象的原因和解决这一难题的对策
At the same time of the great development o
创新是一切工作长期发展的基础,习近平同志提出创新、创新、再创新的战略,可见创新对于建设与发展的价值。档案管理同样需要创新来实现提升,只有通过创新才能使档案管理更能
在物理教学中结合物理产生原理融入向善教育，不仅可以丰富课堂教学，而且能健全学生的人格，而且帮助培养学生高尚的道德情怀，让学生在物理学习中树立正确的世界观、人生观、价值观
A highly sensitive, selective, and precise ultra-performance liquid chromatography tandem mass spectrometry method was developed and validated for simultaneous
In this work, the nickel-aluminum layered double hydroxide (Ni-Al LDH) with nitrate interlayer anion was synthesized and used as a solid phase extraction sorben
A new impurity was detected during high performance liquid chromatographic (HPLC) analysis of eslicarbazepine acetate active pharmaceutical ingredient. The stru