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妊娠性滋养细胞肿瘤(GTN)侵犯中枢神经系统(CNS)者约占10%,对有CNS侵犯的GTN患者进行回顾性分析,以期提高治疗效果。 选择1978~1993年在Hacettepe大学医院就诊的7例有CNS转移的GNT患者,占同期GTN患者的14%(7/50)。平均年龄为28.7岁(20~34岁),其中5例开始就有CNS受侵的现象,其余2例在治疗过程中出现脑转移,最常出现的症状为头痛、运动功能丧失、恶心及呕吐等。本组病例中4例是经清宫术
Gestational trophoblastic tumors (GTN) invade the central nervous system (CNS), about 10% of patients with CNS-inflicted GTN were retrospectively analyzed in order to improve the treatment effect. Seven GNT patients with CNS metastases from 1978 to 1993 at Hacettepe University Hospital accounted for 14% (7/50) of patients with GTN during the same period. The mean age was 28.7 years (range, 20-34 years). Of the 5 cases, CNS involvement was observed at the beginning of the study. The remaining 2 cases had brain metastases during treatment. The most common symptoms were headache, loss of motor function, nausea and vomiting Wait. In this group of 4 cases by the curettage