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目的比较腹腔镜手术与开腹手术治疗早期宫颈癌的临床效果。方法 100例宫颈癌患者,按照数字随机原则将患者分成实验组和对照组,每组50例。对照组患者选择传统经腹宫颈癌根治术治疗,实验组患者选择腹腔镜宫颈癌根治术治疗,比较两组患者的临床疗效。结果实验组手术时间显著长于对照组(P<0.05);实验组术中出血量、淋巴结清扫数目、术后排气时间、住院时间以及术后并发症发生率显著优于对照组(P<0.05)。术后对患者进行为期3年的随访发现,对照组患者3年生存率为44.0%(22/50),3年癌症患者生命质量测定量表(FACT-G)评分为(70.7±9.4)分;实验组患者3年生存率为48.0%(24/50),3年FACT-G评分为(86.8±10.1)分;两组患者术后3年生存率比较差异无统计学意义(P>0.05);实验组术后3年FACT-G评分显著高于对照组(P<0.05)。结论在对早期宫颈癌患者进行治疗时,腹腔镜手术治疗具有微创、术后恢复时间短、并发症发生率低等优点,能有效提高患者的长期生存质量。
Objective To compare the clinical effects of laparoscopic surgery and laparotomy in the treatment of early cervical cancer. Methods 100 cases of cervical cancer patients, according to the principle of random numbers were divided into experimental group and control group, 50 cases in each group. The patients in the control group were treated with radical transabdominal cervical cancer radical resection. The patients in the experimental group were treated by laparoscopic radical resection of cervical cancer. The clinical effects were compared between the two groups. Results The operation time of the experimental group was significantly longer than that of the control group (P <0.05). The bleeding volume, number of lymph node dissection, postoperative exhaust time, hospital stay and postoperative complications in the experimental group were significantly better than those in the control group ). After 3-year follow-up, the 3-year survival rate was 44.0% (22/50) in the control group and 70.7 ± 9.4 in the 3-year cancer patient’s life quality assessment scale (FACT-G) . The 3-year survival rate was 48.0% (24/50) in the experimental group and 86.8 ± 10.1 in the 3-year FACT-G group. There was no significant difference in the 3-year survival rates between the two groups (P> 0.05 ). The FACT-G score of the experimental group at 3 years after operation was significantly higher than that of the control group (P <0.05). Conclusion In the treatment of patients with early cervical cancer, laparoscopic surgery has the advantages of minimally invasive, short recovery time and low complication rate, which can effectively improve the long-term quality of life of patients.